RESEARCH

Helical Polymers: Structure and Function

It is known that there is a strong function/structure relationship in biomolecules, and therefore non natural helical polymers are expected to show a similar behavior. In our group we work with dynamic helical polymers. These molecules are very interesting due to the possibility of modulate their helical sense by the action of external stimuli on the pendant groups. Thus, changes on the pendant conformation are transferred to the helical backbone producing different effects such as chiral amplification or helical inversion.

Structure helix

Structure 2

 

See:

 Nanoscale, 2016,  DOI: 10.1039/C5NR07990J.

Chem. Sci. 20145, 2170-2176. 

Chem. Sci., 20134, 2735-2743.

Angew. Chem. Int. ed. 201150, 11692-11696.

 

Chiral Nanostructures

Polymer particles are a family of nanostructures based on polimeric materials. In our group we are interested in prepare these materials by using dynamic helical polymers. Thus, macroscopically chiral nanostructure can be obtained and their chirality at the macroscopic level can be tuned by the presence of external stimuli.

 

chiral nano

See:

Small, 201612, 238-244

Chem. Sci., 20156, 246–253

Angew. Chem. Int. Ed. 201453, 13720-13724.

J. Am. Chem. Soc. 2012134, 19374-19383.

 

 

 

 

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